Integrated Services · RNA-seq

RNA-seq data with clinically characterized tissue

Select oncology tissue from TriStar’s repository with the treatment history and follow-up relevant to your RNA-seq study. Explore cohorts with optional expression datasets, or discuss additional RNA profiling on selected specimens.

H&E-stained tissue microarray from the TA4301 NSCLC collection
NSCLC tissue microarray · TA4301

THE INTEGRATED SERVICES APPROACH

Samples, services and pathology expertise through one partner

Repository samples

Selected for your study

ADD AS NEEDED

Assays & platform work

Additional biomarker characterization

Pathology guidance

Pharmaceutical research experience

Fewer handoffs
Spend less time coordinating samples and additional work across providers.
Pathology-informed decisions
Connect tissue suitability, assay selection and interpretation.
Coordinated sample use
Plan tissue allocation and laboratory work together, with one point of contact.

EXPRESSION & CLINICAL CONTEXT

Study gene expression in a defined treatment cohort

NSCLC with second-line immunotherapy follow-up

TA4301 connects a defined NSCLC tissue collection with second-line immuno-oncology follow-up. RNA-seq, GeoMx protein and RNA panels, and DAB IHC data are optional additions to the collection.

Tissue collection
NSCLC tissue microarray
Treatment context
Second-line immunotherapy follow-up
Optional datasets
RNA-seq, GeoMx protein/RNA and DAB IHC
Explore TA4301
H&E-stained NSCLC tissue microarray TA4301
TA4301 · Tissue collection with treatment follow-up and optional molecular datasets.

TISSUE MICROARRAYS

TMAs with treatment follow-up and optional RNA-seq

These tissue microarrays (TMAs) offer optional RNA-seq datasets. Dataset coverage and accompanying clinical fields are reviewed for the array you select.

TMA · TA4301

NSCLC

  • Second-line IO follow-up
  • Optional RNA-seq

Optional GeoMx protein/RNA panels and DAB IHC data can provide further context.

TMA · TA4317

Melanoma

  • Stage III–IV & metastases
  • First- & second-line IO follow-up
  • Optional RNA-seq

Malignant melanoma and metastatic melanoma tissue with treatment follow-up.

DESIGN THE COMPARISON

Connect expression, tissue and treatment records

YOUR SELECTED COHORT

Expression data in its biological context

Specify the comparison before selecting samples: a treatment group, response category or molecularly defined subset.

Explore donor data
Tissue characteristics
Indication, histology and tumor content help define the sampled material.
Clinical annotations
Review the available treatment history, response and follow-up fields.
Molecular context
Consider existing IHC or other molecular findings alongside expression data.

ADD RNA PROFILING

Assess the tissue for the RNA analysis you need

PPIB RNA in situ hybridization control in FFPE tissue
PPIB RNA-ISH control example. RNA-seq suitability requires assessment for the proposed sequencing method.

Pathology review informs sample selection

Review tumor content, tissue composition and necrosis alongside the available RNA quality information. These factors help determine which specimens are appropriate for the planned analysis.

Existing qualification
Selected tissue has RNA-ISH control information; it does not by itself establish RNA-seq suitability.
Additional profiling
Agree the RNA assay, specimen requirements and data outputs for the selected tissue.

Work with our experienced scientific team to tailor biospecimens, data, and integrated services to your research needs.

Our approach begins with our customers’ science.

We focus our acquisition on patient cohorts that meet the needs of biopharma, clinical, and translational researchers.

Scientist working with a pipette in a laboratory

Plan your study

Build a tissue cohort for RNA-seq research

Share your indication, treatment or outcome groups, cohort size and tissue requirements. We’ll review repository cases and available datasets, and discuss additional RNA profiling where needed.

Request a cohort