Human biological samples · Oncology repository

Human biospecimens for oncology research

Select FFPE tissue, tissue microarrays and matched plasma for your study. Explore treatment-defined and molecularly characterized cohorts, with clinical records and whole-slide images available from our translational pathology repository.

Gloved hands preparing tissue at a paraffin embedding station
TriStar · Translational pathology repository

Explore biospecimens for your study

High quality tissues deliver high quality research

Choose the sample format, then explore the cohorts and accompanying data available for your research.

Archived FFPE tissue cassettes arranged in a laboratory
FFPE tissue blocks

Surgical tissue

FFPE blocks, sections & curls

Select primary tumors, metastases or normal tissue with the clinical and molecular characteristics your study requires. Explore pre-defined cohorts or discuss a selection built around your protocol.

  • Treatment-defined cohorts
  • Molecular characterization
  • Matched tissue options
H&E-stained tissue microarray showing an array of tissue cores
Representative H&E-stained tissue microarray

Tissue microarrays

TMA blocks & slides

Evaluate biomarkers across multiple tissue cores on a single slide. Browse established oncology TMAs with collection-specific characterization, or discuss a custom array for your study.

  • Multi-tumor arrays
  • Indication-specific TMAs
  • Custom array design
Illustrative laboratory scene of plasma aliquots and matched FFPE tissue blocks
Matched plasma & tissue · Illustrative scene

Matched specimens

Double-spun plasma & FFPE tissue

Investigate circulating biomarkers alongside matched tumor tissue. Explore paired collections across eight cancer indications, with plasma or whole blood and FFPE tissue from the same donor.

  • Matched plasma & tissue
  • Eight cancer indications

The featured paired collection is sourced from Ukraine and does not include outcome data.

Clinical & molecular context

Select tissue with the donor profiles your study needs

Build FFPE cohorts around disease characteristics, treatment history and available follow-up. Our tissue repository includes surgical specimens from participating medical centers in the UK, Italy and France, collected with informed consent and ethics approval.

Breadth of donor profiles

Specimen, treatment, outcomes and molecular data, structured at the patient level.

Patient trajectory

  • Primary tumors & matched distant metastases
  • Matched normal tissue
  • Neoadjuvant & adjuvant treatment
  • Standard-of-care targeted therapies & checkpoint inhibitors
  • Treatment regimen, line & dates
  • Responders & non-responders

Structured outcomes

  • Clinician-recorded response
  • Overall survival (months)
  • Progression-free survival (months)
  • Time to events (months)
  • Last follow-up
  • Event flags: recurrence / death / composite

Molecular characterization

  • IHC
  • FISH
  • RNA-ISH
  • NGS: SNVs, CNVs & fusions

Treatment context

  • Checkpoint inhibitors & IO
  • Antibodies & ADCs
  • Kinase inhibitors
  • CDK4/6 inhibitors
  • PI3K/mTOR inhibitors
  • PARP inhibitors

Records are fully anonymized. Available fields vary by donor and reflect clinical practice at the source center. Cohorts are selected to meet your project’s requirements.

TISSUE COLLECTIONS

Explore tissue collections
by indication

Collections
31
TMAs in these collections
271
FFPE cohort profiles
63

Compare tissue microarrays and documented FFPE cohort profiles. Open a collection to explore the tissue, patient profiles and associated data.

Bladder cancer
TMAs
16
FFPE cohort profiles
2
Explore collection
Breast cancer
TMAs
27
FFPE cohort profiles
7
Explore collection
Cervical cancer
TMAs
5
FFPE cohort profiles
0
Explore collection
Cholangiocarcinoma
TMAs
5
FFPE cohort profiles
0
Explore collection
Colorectal cancer
TMAs
62
FFPE cohort profiles
6
Explore collection
Cutaneous SCC
TMAs
4
FFPE cohort profiles
2
Explore collection
Endometrial cancer
TMAs
13
FFPE cohort profiles
4
Explore collection
Esophageal cancer
TMAs
5
FFPE cohort profile
1
Explore collection
Gallbladder cancer
TMAs
2
FFPE cohort profiles
0
Explore collection
Gastric cancer
TMAs
17
FFPE cohort profiles
3
Explore collection
Gastrointestinal stromal tumors
TMAs
4
FFPE cohort profile
1
Explore collection
Glioblastoma (GBM)
TMAs
7
FFPE cohort profile
1
Explore collection
Head and neck cancer
TMAs
23
FFPE cohort profiles
3
Explore collection
Hematological cancers
TMAs
16
FFPE cohort profile
1
Explore collection
Idiopathic pulmonary fibrosis (IPF)
TMA
1
FFPE cohort profiles
0
Explore collection
Liver cancer (HCC)
TMAs
11
FFPE cohort profiles
4
Explore collection
Lung cancer
TMAs
53
FFPE cohort profiles
13
Explore collection
Melanoma
TMAs
15
FFPE cohort profiles
2
Explore collection
Mesothelioma
TMAs
5
FFPE cohort profiles
0
Explore collection
Multi-tumor
TMAs
33
FFPE cohort profiles
0
Explore collection
Neuroendocrine tumors
TMAs
4
FFPE cohort profiles
0
Explore collection
Normal tissue
TMAs
31
FFPE cohort profiles
0
Explore collection
Ovarian cancer
TMAs
18
FFPE cohort profiles
4
Explore collection
Pancreatic cancer
TMAs
16
FFPE cohort profile
1
Explore collection
Prostate cancer
TMAs
22
FFPE cohort profiles
5
Explore collection
Renal cell carcinoma
TMAs
14
FFPE cohort profiles
3
Explore collection
Sarcoma
TMAs
6
FFPE cohort profiles
0
Explore collection
Small bowel cancer
TMAs
4
FFPE cohort profiles
0
Explore collection
Testicular cancer
TMA
1
FFPE cohort profiles
0
Explore collection
Thyroid cancer
TMAs
6
FFPE cohort profiles
0
Explore collection
Upper urinary tract urothelial cancer
TMAs
3
FFPE cohort profiles
0
Explore collection

TMA counts show cataloged arrays; FFPE counts show documented cohort profiles. Counts do not indicate sample quantities or current availability. Other FFPE tissue requirements can be discussed with our team.

Representative H&E section of colon adenocarcinoma
Representative H&E-stained tissue

Image & clinical data repository

Whole-slide images linked to the source tissue

Explore more than 100,000 H&E whole-slide images from 30,000 donors, linked to anonymized clinical records and archived FFPE tissue.

Select cases by tumor type, treatment and outcome for computational pathology and translational oncology research.

Assays & pathology support

Integrated tissue assay services

Pair selected FFPE tissue and TMAs with assays and pathology guidance, planned around your study.

Protein expression

IHC assay services

Add protein-expression measurements with 100+ optimized IHC assays, or discuss assay development for a new target.

Explore IHC services

Spatial RNA expression

RNAscope RNA-ISH

Localize target RNA in FFPE tissue, with pre-qualified samples, assay controls and pathologist scoring.

Explore RNAscope

Multiplex protein imaging

Multiplex immunofluorescence

Study protein co-expression, cell phenotypes and spatial relationships in selected FFPE tissue and TMAs.

Explore multiplex IF

100+ optimized IHC assays

Selected targets from the IHC library. Multiplex panels are reviewed separately.

Browse the IHC target library →

Growth factor signaling

IHC staining on Ventana and Dako platforms. Review and scoring by medical pathologists with pharmaceutical industry experience.

Work with our experienced scientific team to tailor biospecimens, data, and integrated services to your research needs.

Our approach begins with our customers’ science.

We focus our acquisition on patient cohorts that meet the needs of biopharma, clinical, and translational researchers.

Scientist working with a pipette in a laboratory

Plan your study

Tell us the cohort your study needs

Share your cancer indication, donor count, sample format and clinical or molecular criteria. We’ll review suitable repository specimens, available data and any additional work your study requires.

Request a cohort