Expedite Your Biomarker Research With Our Integrated Services

Full Service Solutions Tailored To Your Project Needs

A Single Entity for Samples and Contract Research

We will sit down with you and work out exactly what the objective of your project is as well as the parameters to work within.

In addition to any samples provided from your labs we will source the right samples from within our repositories and network.

We will make sure we can put together the right team and platforms to complete your project correctly and on time.

We will confirm that the samples we've collected & services platform we've created meet your needs and start the project upon your deposit.

We will keep you appraised of anything that comes up within the project that requires your decision, input, or notice.

We will package all required physical deliverables and send them via expedited shipping. Digital files that will be sent securely via email.

Our Experts

Depth of
Pathology Expertise

Our team of pathology experts come from academia, large pharma, and large medical institutions around the globe.
  • 4 MD Pathologists
  • Expertise in TMA scoring
  • IHC, FISH/CISH, RNAscope
  • ISO9001 Accredited Labs
  • Over 100 Assays
  • Assay transfer and validation

Our Capabilities

Immunohistochemistry Services

We have been involved with TMA manufacture and IHC analysis for over 10 years. We have an in-house repository of over 50,000 FFPE blocks that have been pre-selected for IHC studies. Our pathologists can score series of TMAs with an aggregate of over 1000 one millimeter cores rapidly and accurately. We specialize in optimizing challenging IHC protocols and can attempt protocol development when only the target(s) are specified.
  • Ventana Benchmark Ultra
  • Dako
  • Leica Bond Max
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Sanger & Next Generation Sequencing

We offer fit for purpose solutions using Sanger or NGS (Illumina MiSeq & ThermoFisher S5). We run standard Illumina and ThermoFisher NGS panels and offer customized panels. Customers can opt to do all or part of the screening at their site(s) in which case we transfer sections or extracted RNA/DNA and reserve the corresponding blocks for 30 days.
  • Oncomine Focus Assay
  • Oncomine cfNA Assays
  • TruSight Tumor 15
  • TruSight Tumor 170
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RNAscope

In addition to testing specific FFPE blocks and constructing RNAscope pre-qualified TMAs (2.5 HD Assay), we offer RNAscope services on all our FFPE samples and TMAs. This is a valuable addition to our core IHC capabilities as RNAscope addresses biomarkers where suitable IHC antibodies are unavailable. We are currently working on RNAscope, IHC and other platforms to study:
  • EGFRvIII Splice Variant
  • Immuno-oncology
  • Lung Cancer
  • Prostate Cancer
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Digital Image Analysis

We can create digital scans of stained TMA and whole tissue sections in multiple formats. Scanned images allow for efficient, effective and rapid shared pathology reviews within projects and for computerized analysis which offers reliable, consistent and automated quantification of the more complex cellular interactions. Combined with TriStar’s IHC expertise and development of specific assays our digital image analysis service provides a powerful tool in the spatial investigation of the tumour microenvironment including immuno-oncology.
  • Leica
  • Hamamatsu
  • Indica Labs Halo
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