Accelerate your oncology R&D with quality biospecimens & data

Our biospecimen repository is purpose-built to accelerate oncology therapeutic development.

We are a key resource for

Pharma & biotech

High-quality clinical specimens for biomarker research, with available histopathology, molecular characterization and treatment follow-up.

Diagnostics companies

Specimens and control tissues for histologic and nucleic-acid assays, including IHC, NGS and multiplex assay development.

Paper · Citation · npj Precision Oncology · 2025

The development of a high-plex spatial proteomic methodology for the characterisation of the head and neck tumour microenvironment (opens in a new tab)

AI companies

Whole-slide H&E images, associated clinical records and source tissue for computational pathology and algorithm development.

Paper · Citation · Journal of Translational Medicine · 2024

Spatial insights into immunotherapy response in non-small cell lung cancer (NSCLC) by multiplexed tissue imaging (opens in a new tab)

Organizations are identified from author affiliations, patent records and report credits. Their inclusion does not imply a partnership with or endorsement of TriStar.

Samples. Donor data. Matched images.

TriStar’s Oncology Translational Pathology Repository

Ethically sourced

Informed consent and ethics approval support our established tissue collections.

Quality assurance

Medical pathologists help assess tissue suitability for your study.

Paraffin tissue blocks arranged in a laboratory

FFPE tissue & cohorts

Linked donor data

Select primary, metastatic and non-malignant tissue by indication, biomarker profile and treatment history.

Explore FFPE cohorts19cohort
indications
H&E-stained tissue microarray

Tissue microarrays

Linked donor data

Explore multi-tumor, normal tissue and indication-specific TMAs, including selected treatment-linked collections.

Browse TMAs160TMAs in
the catalog
Gloved hand holding a tube with separated plasma

Matched plasma & tissue

Linked donor data

Double-spun plasma with matched FFPE tissue in selected collections, with buffy coat requirements discussed for your study.

Explore matched plasma8paired-collection
indications
H&E section of colon adenocarcinoma

Linked across our sample collections

Images & clinical data

FFPE tissue, TMAs and matched plasma connect to clinical and molecular records from the same donors.

  • Treatment history & recorded response
  • Survival & clinical follow-up
  • Clinical & molecular characterization
Donors in the image repository
30,000+
H&E whole-slide images
100,000+
Scanning magnification
40×
Image file format
.SVS

Records are anonymized. Sample matching and available data vary by donor and collection.

Tissue microarrays

An expansive collection of unique Tissue Microarrays

Scientifically relevant tissue microarrays developed from strategically collected human tissue and research collaborations. Explore collections with treatment follow-up and molecular data, including selected RNAscope-prequalified arrays.

  • Collection breadthMulti-tumor, normal tissue, tumor-specific and variant-specific TMAs
  • Clinical follow-upTreatment, response and survival information in selected collections
  • Molecular contextSelected arrays with IHC, NGS or RNA-seq data
Explore tissue microarrays
Spatial analysis of NSCLC tissue from immunotherapy responders and non-responders
Spatial analysis of a pre-treatment NSCLC cohort with second-line immunotherapy response data, using the Akoya MOTiF™ lung cancer PD-1/PD-L1 panel. Representative cores compare responders and non-responders; the plot examines cellular interactions.

Beyond the specimen

Anonymized donor records with clinical & molecular data

Specimen, treatment, outcomes and molecular data, structured at the patient level. Select cases using the clinical history and follow-up relevant to your research.

Patient trajectory

  • Primary tumors & matched distant metastases
  • Matched normal tissue
  • Neoadjuvant & adjuvant treatment
  • Standard-of-care targeted therapies & checkpoint inhibitors
  • Treatment regimen, line & dates
  • Responders & non-responders
  • Treatment-naïve & treated cases

Structured outcomes

  • Clinician-recorded response
  • Overall survival (months)
  • Progression-free survival (months)
  • Time to events (months)
  • Last follow-up
  • Event flags: recurrence / death / composite

Molecular characterization

  • IHC
  • FISH
  • RNA-ISH
  • NGS: SNVs, CNVs & fusions

Treatment context

  • Checkpoint inhibitors & IO
  • Antibodies & ADCs
  • Kinase inhibitors
  • CDK4/6 inhibitors
  • PI3K/mTOR inhibitors
  • PARP inhibitors

The integrated services approach

Samples, services and pathology expertise through one partner

Add laboratory services and pathology guidance to your repository request, coordinated around your study.

Start with the right samples

Repository tissue selected for your research, with assays and platform work added as needed.

Pathologists with pharma experience

Our medical pathologists guide your project from study planning through completion, advising on tissue selection, assay strategy and interpretation.

Coordinated tissue use and testing

Plan tissue allocation and laboratory work together, with one point of contact from sample selection through analysis.

Define your study

Assays & pathology support

Choose the assays your study needs

Assay development, staining and pathology scoring, guided by pharmaceutical research experience.

Protein expression

IHC assay services

Add protein-expression measurements with 100+ optimized IHC assays, or discuss assay development for a new target.

Explore IHC services

Spatial RNA expression

RNAscope RNA-ISH

Localize target RNA in FFPE tissue, with pre-qualified samples, assay controls and pathologist scoring.

Explore RNAscope

Multiplex protein imaging

Multiplex immunofluorescence

Study protein co-expression, cell phenotypes and spatial relationships in selected FFPE tissue and TMAs.

Explore multiplex IF

Additional profiling & analysis

Add molecular profiling or image analysis to your repository request.

Time

Fewer handoffs

Spend less time coordinating samples and laboratory work across providers.

Expertise

Pathology-informed decisions

Connect tissue suitability, assay selection and interpretation.

Logistics

Coordinated sample use

Plan tissue allocation and additional work with one point of contact.

Plan your study

Define your study

Tell us what your research needs. Our team will help you plan the right combination of samples, data and laboratory services.

Start with your study requirements

  • Cancer indication and study objective
  • Sample format and approximate cohort size
  • Clinical data, images or assays you need

You don’t need a complete specification to start a conversation.

Contact our team

Work with our experienced scientific team to tailor biospecimens, data, and integrated services to your research needs.

Our approach begins with our customers’ science.

We focus our acquisition on patient cohorts that meet the needs of biopharma, clinical, and translational researchers.

Scientist working with a pipette in a laboratory

Plan your study

Define your cohort and study requirements

Share your indication, sample format, cohort size and required clinical or molecular information. Our team will help you explore the relevant collections and additional work.

Discuss your study