Integrated Services Digital Image Analysis

Digital Image Analysis

Quantify biomarker expression in whole slide digital images.

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TriStar offers quantitative digital pathology services for integrated projects to enumerate and localize target expression in TMAs & whole tissue sections. Digital image analysis is assisted throughout by TriStar’s medical pathologists to ensure evaluation of relevant regions of interest, optimal algorithm performance and data interpretation.

Our Team is experienced in digital image analysis of TMAs and correlation with molecular and clinical annotations.

Benefits of choosing Tristar’s services

Whole slide scanner

TriStar provides whole slide digital images for all integrated service projects.

Digital pathology services

TriStar utilizes open source image analysis solutions (QuPath & CellProfiler) in addition to Indica Labs Halo image analysis platform.

4MD Pathologists

TriStar delivers pathologist-assisted digital image analysis to generate biologically relevant biomarker data.

Digital Spatial Profiling

Analyze targets & spatial relationships in context of TME with CODEX & Nanostring GeoMx DSP.

Service Workflow

Define Your Project Requirements
We will sit down with you and work out exactly what the objective of your project is as well as the parameters to work within.
Sample Allocation
We will source the right samples from within our repositories and network.
Services Platform
We will put together the right team and platforms to complete your project correctly and on time.
Confirm & Start Project
A Statement of Work that includes a project plan, deliverables, costs and timelines will be discussed and agreed upon.

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Related Services

IHC Services

Our experienced ex-pharma scientists & pathologists specialize in IHC assay development, and protocol optimization & analysis to deliver robust data while accelerating project decisions.

Prevalence Studies

TriStar’s services can be used to guide patient selection for projects & inform the path to clinical development. TMAs and/or FFPE blocks can be combined into sets to screen 150-1500 donor samples per indication.

Publications

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Ultivue & OracleBio June 2022 ASCO 2022 June-2022

Analysis of the contribution of macrophages to the overall tumor PD-L1 microenvironment using a screening multi-tumor tissue microarray and rapid multiplex fluorescence digital phenotyping approach.

Seoul National University Medical College April 2023 AACR 2023 Apr-23

Relative contribution of tumor infiltrating B cells to the tumor microenvironment assessed using an immuno-oncology focused multi-tumor tissue microarray.