Digital image analysis for tissue biomarker studies
Build your image analysis study around TriStar’s oncology tissue, linked whole-slide images and available donor records. Select a clinically defined cohort and add staining, quantitative image analysis or pathology support as needed.
THE INTEGRATED SERVICES APPROACH
Samples, services and pathology expertise through one partner
Repository samples
Selected for your study
- Fewer handoffs
- Spend less time coordinating samples and additional work across providers.
- Pathology-informed decisions
- Connect tissue suitability, assay selection and interpretation.
- Coordinated sample use
- Plan tissue allocation and laboratory work together, with one point of contact.
FROM STAINING TO MEASUREMENTS
Quantify the cells and tissue regions that matter
Expression
Quantify marker-positive cells and staining patterns for the assay being studied.
Cell phenotypes
Identify populations using the markers and combinations included in the panel.
Tissue compartments
Assess selected regions, including tumor and stromal compartments.
Cohort comparisons
Relate measurements to the molecular and clinical annotations available for the selected cases.
PATHOLOGY-ASSISTED ANALYSIS
Define the readout around the specimen and stain
Relevant regions. Reviewed measurements.
TriStar’s medical pathologists support region selection, review of analysis results and interpretation in the context of tissue morphology.
Agree the measurements before analysis, including the marker, cell population, tissue compartment and reporting unit relevant to the study.
- Analysis tools
- Workflows include QuPath, CellProfiler and HALO. The approach is selected for the assay and project.
- Tissue formats
- Whole-tissue sections and tissue microarrays.
- Study outputs
- Quantitative measurements and pathology input scoped to the research question.
TISSUE MICROARRAYS
TMAs for immuno-oncology and treatment studies
Explore tissue microarrays (TMAs) with the histopathology, treatment and follow-up information relevant to your comparison.
Multi-tumor IO array set
A set of six TMAs with 1 mm cores from tumor and invasive-edge regions.
NSCLC
Optional RNA-seq, GeoMx protein/RNA and DAB IHC data.
Head & neck SCC
An indication-specific collection with immunotherapy follow-up information.
Ovarian cancer
Pre- and post-treatment groups are not donor matched.
Research & references
Research using TriStar tissue and data
Author affiliations
Ultivue
OracleBio
+1 more organizations
TriStar Technology Group
Organizations are identified from author affiliations, patent records and report credits. Their inclusion does not imply a partnership with or endorsement of TriStar.
Study cohort reported in the poster: 11 tumor types, 144 donors and 288 tissue cores.
IMAGE DATA OR IMAGE ANALYSIS?
Access existing images, or add quantitative measurements
The Image & Clinical Data repository provides whole-slide images linked to donor records and source tissue. Digital image analysis adds measurements to images for a defined biomarker study.
Explore Image & Clinical DataWork with our experienced scientific team to tailor biospecimens, data, and integrated services to your research needs.
Our approach begins with our customers’ science.
We focus our acquisition on patient cohorts that meet the needs of biopharma, clinical, and translational researchers.
Plan your study
Build your image analysis cohort
Share your indication, biomarker, cohort size and tissue or image requirements. We’ll review repository options and available donor data, then scope any additional staining, image analysis or pathology support you need.