Advances in molecular methods have greatly facilitated the discovery of potential molecular targets for therapy. Accelerated lead discovery has at the same time generated a massive demand for thorough validation of such putative targets. Human tissue analysis is needed for this purpose. However, the need to analyze large numbers of well- characterized human tissues constitutes a major bottleneck in drug discovery and development. Tissue Micro Arrays address this by enabling the simultaneous analysis of thousands of tissue samples in a single experiment under uniform conditions.

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